The Rare Disease Database

The most comprehensive source of rare disease information.

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Top 10 rare neurological diseases

Measured by: prevalence

DiseaseEst US prevalenceInheritanceAge of onset
Narcolepsy150,000 - 200,000
Lennox-Gastaut syndrome45,000 – 50,000
Young onset parkinson’s disease40,000 – 45,000
Tuberous sclerosis27,000 – 37,500
Huntington disease22,750 – 35,000
Tibial muscular dystrophy19,500 – 30,000
Amyotrophic lateral sclerosis17,000 – 30,000
Duchenne’s muscular dystrophy15,000 – 20,000
Congenital muscular dystrophy15,000 – 20,000