Rare Dermatology News

Disease Profile

Eccrine porocarcinoma

Prevalence estimates on Rare Medical Network websites are calculated based on data available from numerous sources, including US and European government statistics, the NIH, Orphanet, and published epidemiologic studies. Rare disease population data is recognized to be highly variable, and based on a wide variety of source data and methodologies, so the prevalence data on this site should be assumed to be estimated and cannot be considered to be absolutely correct.


US Estimated

Europe Estimated

Age of onset





Autosomal dominant A pathogenic variant in only one gene copy in each cell is sufficient to cause an autosomal dominant disease.


Autosomal recessive Pathogenic variants in both copies of each gene of the chromosome are needed to cause an autosomal recessive disease and observe the mutant phenotype.


dominant X-linked dominant inheritance, sometimes referred to as X-linked dominance, is a mode of genetic inheritance by which a dominant gene is carried on the X chromosome.


recessive Pathogenic variants in both copies of a gene on the X chromosome cause an X-linked recessive disorder.


Mitochondrial or multigenic Mitochondrial genetic disorders can be caused by changes (mutations) in either the mitochondrial DNA or nuclear DNA that lead to dysfunction of the mitochondria and inadequate production of energy.


Multigenic or multifactor Inheritance involving many factors, of which at least one is genetic but none is of overwhelming importance, as in the causation of a disease by multiple genetic and environmental factors.


Not applicable


Other names (AKA)

Porocarcinoma; Eccrine porocarcinoma of skin; Malignant eccrine poroma


Rare Cancers


Eccrine porocarcinoma is a rare type of skin cancer that may occur by chance or may develop from a benign (non-cancerous) skin tumor. They affect the eccrine sweat glands, which are the major sweat glands of the body. Eccrine porocarcinoma usually are found in adults older than 60 and appear as a single red elevated solid mass (nodule) or a thickened or elevated lesion (plaque). They are found anywhere on the body, but occur most commonly on the lower limbs, head, and upper limbs.[1][2] Most people with an eccrine porocarcinoma do not have symptoms; however some individuals may notice bleeding from the tumor or itching.[2] Factors that may increase the risk to develop an eccrine porocarcinoma include family history, suppression of the immune system, and exposure to ultraviolet light or radiation.[3] Treatment usually involves surgery to remove the tumor.[1]

Learn more

These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.

Where to Start

  • DermNet NZ is an online resource about skin diseases developed by the New Zealand Dermatological Society Incorporated. DermNet NZ provides information about this condition.

In-Depth Information

  • Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.


  1. Abdulwahid M. Saliha, F.H. Kakamadb, Rawand A. Essac, Goran M. Raufd, Masrur S.A, Shvan H.M., Rawezh Q.S., Hunar A.H., Dahat A.H., Snur Othmane. Porocarcinoma: A systematic review of literature with a single case report. International Journal of Surgery Case Reports. 2017; 30:13-16. https://www.sciencedirect.com/science/article/pii/S2210261216304485.
  2. Kenneth Wong. Eccrine porocarcinoma. DermNet New Zealand. 2008; https://www.dermnetnz.org/topics/eccrine-porocarcinoma/. Accessed 12/13/2016.
  3. Ferzli, GM., Doyle, AK., Hui, AM., Lindgren, A. Eccrine Carcinoma. Medscape. September 22, 2016; https://emedicine.medscape.com/article/1101796. Accessed 12/13/2016.